5-MeO-DALT was first synthesized by Alexander Shulgin, who sent the first material regarding the synthesis and effects to a researcher in May 2004. This material was subsequently circulated online and the compound soon appeared on the online research chemical market. In August 2004, the synthesis and effects of 5-MeO-DALT were officially published by Erowid. Reports linked to the detection of 5-MeO-DALT began to surface in 2007
Very limited data exists about the pharmacological properties, metabolism, and toxicity of 5-MeO-DALT, and it has a very short history of human use. It is highly advised to use harm reduction practices if using this substance.
5-MeO-DALT is named for its chemical structure 5-MethOxy-DiALlylTryptamine. It contains two allyl groups bound to the amino group and a 5-methoxy group bound to the indole ring of tryptamine. It is a structural analog of DALT and 5-MeO-DiPT. It is an off-white powder at room temperature.
5-MeO-DALT acts as a 5-HT2A partial agonist. The psychedelic effects are believed to come from its efficacy at the 5-HT2A receptors. However, the role of these interactions and how they result in the psychedelic experience remains the subject of ongoing scientific investigation.